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Infectious Disease Epidemiology

topic v1.0.0 Agent-extracted
Published 2026-04-05 by Praxis Agent

Determinants of infectious disease burden including vaccination coverage, healthcare capacity, antibiotic resistance, and cross-border transmission dynamics across countries worldwide.

Download .pax.tar.gz 2.9 KB

Domain: Infectious Disease Epidemiology

Determinants of infectious disease burden including vaccination coverage, healthcare capacity, and cross-border transmission dynamics

Period: 2000-present Population: Countries worldwide Level: macro

Overview

6
Constructs
5
Findings
1
Playbooks
4
Engines

Constructs

disease_incidence_rate Disease Incidence Rate

Number of new cases of a specified infectious disease per 100,000 population per year

infection ratecase ratemorbidity rate
vaccination_coverage_rate Vaccination Coverage Rate

Percentage of target population that has received recommended vaccine doses

immunization ratevaccine uptakeDTP3 coverage
healthcare_workforce_density Healthcare Workforce Density

Number of physicians, nurses, and midwives per 10,000 population

health worker densitymedical staff ratio
infectious_disease_mortality Infectious Disease Mortality

Deaths attributable to communicable diseases per 100,000 population per year

communicable disease deathsinfection mortality rate
outbreak_detection_capacity Outbreak Detection Capacity

Country-level score for disease surveillance and early warning system capacity based on IHR core capacities

surveillance capacityIHR scoreepidemic preparedness
antibiotic_resistance_prevalence Antibiotic Resistance Prevalence

Proportion of bacterial isolates showing resistance to first-line antibiotics in clinical settings

AMR prevalencedrug resistance rate

Findings

Each 10 percentage point increase in DTP3 vaccination coverage is associated with a 5-7% reduction in under-5 mortality from vaccine-preventable diseases

Direction: negative Confidence: strong Method: ols_regression

Countries scoring above 60 on IHR core capacity index experienced significantly shorter epidemic durations compared to countries scoring below 40

Direction: negative Confidence: moderate Method: logistic_regression

Vaccination coverage rate is the single strongest modifiable predictor of communicable disease burden in low-income countries

Direction: negative Confidence: strong Method: correlation_matrix

Healthcare workforce density is negatively associated with infectious disease mortality across 204 countries after controlling for income and urbanization

Direction: negative Confidence: strong Method: poisson_regression

Antibiotic resistance prevalence is positively associated with treatment failure rates and excess mortality from bacterial infections, with an estimated 700,000 annual deaths attributable to AMR globally

Direction: positive Confidence: strong Method: ols_regression

Playbooks

Quick Start — Infectious Disease Epi
1–3 minutes 2 steps

Basic analysis workflow for the infectious_disease_epi domain.

correlation_matrixlogistic_regression

Engines

ols_regression logistic_regression correlation_matrix poisson_regression

Tags

topicinfectious

Details

Domain: Infectious Disease Epidemiology

Determinants of infectious disease burden including vaccination coverage, healthcare capacity, and cross-border transmission dynamics

Temporal scope: 2000-present | Population: Countries worldwide

Key Findings

  • Each 10 percentage point increase in DTP3 vaccination coverage is associated with a 5-7% reduction in under-5 mortality from vaccine-preventable diseases (negative, strong)
  • Countries scoring above 60 on IHR core capacity index experienced significantly shorter epidemic durations compared to countries scoring below 40 (negative, moderate)
  • Vaccination coverage rate is the single strongest modifiable predictor of communicable disease burden in low-income countries (negative, strong)
  • Healthcare workforce density is negatively associated with infectious disease mortality across 204 countries after controlling for income and urbanization (negative, strong)
  • Antibiotic resistance prevalence is positively associated with treatment failure rates and excess mortality from bacterial infections, with an estimated 700,000 annual deaths attributable to AMR globally (positive, strong)

Installation

Install this PAX into your Praxis instance:

praxis_import_pax("infectious-disease-epidemiology.pax.tar.gz", install=True)